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XML XML is used to store and manage features, components and data, along with their relationships. CAD data A feature containing various types of data can be stored in a drawing, including geometric data, textual data, plot data, annotation data, and other. CAD data can be used to represent components, assemblies, data types, and concepts for simple geometry or more complex engineering drawings. Each of these items can have properties, such as visibility, scale, text, etc., which are set at the time a feature is created. The term CAD data covers the entire set of information a CAD model contains, including the geometry of a component, the contents of files, the relationships between models, entities, and other elements. Geometry Geometric data is stored in.DWG files, while textual data is stored in.DGN files. Plot data is stored in.DWF files, and annotations are stored in.DPA files. These are separate but related, sharing similar formatting requirements, but can vary in content and usage. References External links CAD file formats and their use CAD Data Dictionary (Part A, Part B, Part C) Category:Computer-aided designComprehensive proteome analysis reveals caspase cleavage in rat hypothalamus after acute intracerebroventricular lipopolysaccharide injection. Elevated proinflammatory cytokine levels in blood have been reported in patients with multiple sclerosis (MS), a disease which also affects the hypothalamic-pituitary-adrenal axis (HPA-axis) and the stress response. In addition to the release of cytokines, intracerebroventricular (i.c.v.) administration of lipopolysaccharide (LPS) in mice leads to hypothalamic lesions, HPA-axis activation and a loss of noradrenergic neurons, all of which are associated with the pathogenesis of MS. Because of these findings we determined the hypothalamic proteome profile of rats after i.c.v. injection of LPS. Affinity chromatography of hypothalamic proteins followed by in-solution tryptic digestion and mass spectrometry revealed hypothalamic changes in 40 proteins (24 upregulated, 16 downregulated) in response to LPS administration. Furthermore, all LPS-induced changes were blocked when rats were treated with an NF-κB inhibitor, MG-132, which blocks caspase activation. Therefore, based e315de8065
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